METHODOLOGICAL APPROACHES TO EVIDENCE BASED GUIDELINES IN BURN INJURY Ph.D. Thesis

Quality assessment of clinical practice guidelines for adaptation in burn injury.

OBJECTIVES A number of clinical practice guidelines (CPGs) are available for managing burn injury patients but clinical practice is highly variable. We report the first steps to trans-contextual adaptation of international burn CPGs to local settings. METHODS Key clinical topics and questions to be covered in the final guideline were defined and prioritized. Systematic search between 1990 and...

NEW APPROACHES IN ANALYSIS OF BIOMOLECULES USING CAPILLARY ELECTROPHORESIS –METHODOLOGICAL STUDIES Ph.D. Thesis

“It’s Not Smooth Sailing”: Bridging the Gap Between Methods and Content Expertise in Public Health Guideline Development

Background The development of reliable, high quality health-related guidelines depends on explicit and transparent processes, methods aimed at minimising risks of bias and the inclusion of all relevant expertise and perspectives. While the methodological aspects of guidelines have been a focus to improve their quality, less is known...

Methodological quality of randomised controlled trials in burns care. A systematic review.

OBJECTIVE To evaluate the methodological quality of published randomised controlled trials (RCTs) in burn care treatment and management. METHODS Using a predetermined search strategy we searched Ovid MEDLINE (1950 to January 2008) database to identify all English RCTs related to burn care. Full text studies identified were reviewed for key demographic and methodological characteristics. Metho...

Evaluation of the Quality of Cancer-Related Fatigue Clinical Practice Guidelines

Background: Improvement of the quality ofcancer-related fatigue clinical practice guidelines (CPGs) is an important issue in oncology. Aim: This study aimed to determine the methodological quality of CPGs about cancer-related fatigue management using the AGREE II instrument. Method: This study involved a systematic search, followed by a descriptive study, to evaluate the methodological quality ...